/ Histone type: H2B

H2B is one of the core histones. H2B forms dimers with H2A via the "hand shake" motif. Two H2A-H2B dimers in turn associate with H3-H4 tetramer to form complete nucleosome core. Structure of H2B consists of histone fold with a long flexible N-terminal tail which protrudes between the DNA gyres. H2B interacts with H4 in the nucleosome core via four helix bundle motif. Addtional αC-helix of H2B decorates the surface of nucleosome.
Keys: red - identical residues, blue - different residues (if more than one sequence). For feature legend see summary tab.
Sequence preview and annotation... LOADING

Features characteristic for a given histone type/variant are marked below the consensus sequence. For feature description see summary tabs of the corresponding variants pages.
Keys: red - 80% identical, blue - 50% identical columns. X-ambigous positions in consensus sequence.