/ Histone type: H2A

H2A is one of the core histones. H2A forms dimers with H2B via the "hand shake" motif. Two H2A-H2B dimers in turn associate with H3-H4 tetramer to form complete nucleosome core. Structure of H2A consists of histone fold domain extended by a short αC-helix and has both N- and C-terminal tails. αC-helix and C-terminal tail form "docking domain" that locks the H2A-H2B dimer onto the surface of H3-H4 tetramer.
Keys: red - identical residues, blue - different residues (if more than one sequence). For feature legend see summary tab.
Sequence preview and annotation... LOADING

Features characteristic for a given histone type/variant are marked below the consensus sequence. For feature description see summary tabs of the corresponding variants pages.
Keys: red - 80% identical, blue - 50% identical columns. X-ambigous positions in consensus sequence.